ABCB5

ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]

Full Name

ATP Binding Cassette Subfamily B Member 5

Function

Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair (By similarity).

Biological Process

Cell differentiation
Eye development
Regulation of membrane potential
Transmembrane transport

Cellular Location

Cell membrane

Anti-ABCB5 antibodies

Mouse Anti-ABCB5 Recombinant Antibody (V2-178981) (CBMAB-A0216-YC)

Datasheet

SDS

Target: ABCB5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: V2-178981

Application*: WB, IC, P, C, E

Mouse Anti-ABCB5 Recombinant Antibody (V2-634032) (CBMAB-AP026LY)

Datasheet

SDS

Target: ABCB5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: V2-634032

Application*: IF, IHC, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)