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ABCB5

ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules.

Full Name

ATP Binding Cassette Subfamily B Member 5

Alternative Names

ATP Binding Cassette Subfamily B Member 5; P-Glycoprotein ABCB5; ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5; ATP-Binding Cassette Protein; ABCB5 P-Gp; ATP-Binding Cassette Sub-Family B Member 5;

Function

Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair (By similarity).

Biological Process

Cell differentiation
Eye development
Regulation of membrane potential
Transmembrane transport

Cellular Location

Cell membrane

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Anti-ABCB5 antibodies

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Mouse Anti-ABCB5 Recombinant Antibody (V2-178981) (CBMAB-A0216-YC)

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Target: ABCB5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: V2-178981

Application*: WB, IC, P, C, E

Mouse Anti-ABCB5 Recombinant Antibody (EC1) (V2LY-0624-LY1)

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Target: ABCB5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: EC1

Application*: WB, P, IF

Mouse Anti-ABCB5 Recombinant Antibody (V2-634032) (CBMAB-AP026LY)

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Target: ABCB5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: V2-634032

Application*: IF, IHC, WB

Mouse Anti-ABCB5 Recombinant Antibody (
24G6) (V2LY-0725-LY302)

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Target: ABCB5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 24G6

Application*: E, WB

Mouse Anti-ABCB5 Recombinant Antibody (
12F4) (V2LY-0725-LY46)

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Target: ABCB5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 12F4

Application*: E, WB

Mouse Anti-ABCB5 Recombinant Antibody (CBT1) (V2LY-0625-LY3881)

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Target: ABCB5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBT1

Application*: WB, P, IF, IC

Mouse Anti-ABCB5 Recombinant Antibody (CBT2410) (V2LY-0625-LY2796)

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Target: ABCB5

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBT2410

Application*: IH, IC, F

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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