ACOT7

This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants encoding distinct isoforms with different subcellular locations have been characterized. [provided by RefSeq, Jul 2008]
Full Name
Acyl-CoA Thioesterase 7
Function
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Acyl-coenzyme A thioesterase 7/ACOT7 preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18. May play an important physiological function in brain.
Biological Process
Acyl-CoA metabolic process
Coenzyme A biosynthetic process
Fatty acid metabolic process
Long-chain fatty-acyl-CoA catabolic process
Medium-chain fatty acid biosynthetic process
Medium-chain fatty-acyl-CoA catabolic process
Palmitic acid biosynthetic process
Cellular Location
Isoform 1: Mitochondrion
Isoform 4: Cytosol
Isoform 5: Mitochondrion
Isoform 6: Cytosol
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Anti-ACOT7 antibodies

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Mouse Anti-ACOT7 Recombinant Antibody (V2-179347) (CBMAB-A0648-YC)

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Target: ACOT7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-179347
Application*: E, WB
Datasheet SDS

Mouse Anti-ACOT7 Recombinant Antibody (V2-179346) (CBMAB-A0647-YC)

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Target: ACOT7
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-179346
Application*: E, P, WB
Datasheet SDS

Mouse Anti-ACOT7 Recombinant Antibody (V2-179345) (CBMAB-A0646-YC)

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Target: ACOT7
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-179345
Application*: WB, F, E, IC, IF
Datasheet SDS

Mouse Anti-ACOT7 Recombinant Antibody (V2-179344) (CBMAB-A0645-YC)

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Target: ACOT7
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: V2-179344
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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