AGRP
AGRP is an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutati
Full Name
Agouti Related Neuropeptide
Biological Process
Adult feeding behavior
Circadian rhythm
Eating behavior
Feeding behavior
Hormone-mediated signaling pathway
Long-day photoperiodism
Maternal process involved in female pregnancy
Neuropeptide signaling pathway
Positive regulation of feeding behavior
Regulation of feeding behavior
Response to insulin
Circadian rhythm
Eating behavior
Feeding behavior
Hormone-mediated signaling pathway
Long-day photoperiodism
Maternal process involved in female pregnancy
Neuropeptide signaling pathway
Positive regulation of feeding behavior
Regulation of feeding behavior
Response to insulin
Cellular Location
Secreted; Golgi apparatus lumen
Involvement in disease
Obesity (OBESITY): A condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
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Anti-AGRP antibodies
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CompareTarget: AGRP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: V2-180227
Application*: IC, IH, IP, WB
Target: AGRP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-180226
Application*: WB
Target: AGRP
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: V2-180223
Application*: WB
Target: AGRP
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: V2-180222
Application*: WB, IP
Target: AGRP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: V2-180220
Application*: IH, WB, IC
Target: Agrp
Sensitivity: 0.0052 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: AGRP
Sensitivity: 0.01 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Agrp
Sensitivity: 0.0035 ng/mL
Detection Range: 0.007-1.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: AGRP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 83-132
Tag: Fc Tag
Target: AGRP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-131
Tag: His Tag
Target: AGRP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-131
Tag: hFc Tag
Target: AGRP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 82-131
Tag: hFc Tag
Target: AGRP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-132
Tag: His Tag
Target: AGRP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-132
Tag: hFc Tag
Target: AGRP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 85-132
Tag: hFc Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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