Mouse Agrp ELISA Kit (V2LY-0626-LY1273)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0035 ng/mL
Detection Range
0.007-1.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
14.4 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Agouti Related Neuropeptide
Biological Process
Adult feeding behavior
Circadian rhythm
Eating behavior
Feeding behavior
Hormone-mediated signaling pathway
Long-day photoperiodism
Maternal process involved in female pregnancy
Neuropeptide signaling pathway
Positive regulation of feeding behavior
Regulation of feeding behavior
Response to insulin
Cellular Location
Secreted; Golgi apparatus lumen
Involvement in disease
Obesity (OBESITY): A condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.

Loganathan, N. (2021). Molecular mechanisms involved in the regulation of agouti-related peptide and neuropeptide Y by endocrine disrupting chemical bisphenol A in hypothalamic neurons (Doctoral dissertation, University of Toronto (Canada)).

Qiu, J., Bosch, M. A., Zhang, C., Rønnekleiv, O. K., & Kelly, M. J. (2020). Estradiol protects neuropeptide Y/agouti-related peptide neurons against insulin resistance in females. Neuroendocrinology, 110(1-2), 105-118.

Kalananthan, T., Murashita, K., Rønnestad, I., Ishigaki, M., Takahashi, K., Silva, M. S., ... & Gomes, A. S. (2020). Hypothalamic agrp and pomc mRNA Responses to Gastrointestinal Fullness and Fasting in Atlantic Salmon (Salmo salar, L.). Frontiers in physiology, 11, 61.

Jiang, J., Morgan, D. A., Cui, H., & Rahmouni, K. (2020). Activation of hypothalamic AgRP and POMC neurons evokes disparate sympathetic and cardiovascular responses. American Journal of Physiology-Heart and Circulatory Physiology, 319(5), H1069-H1077.

Chen, Y., Essner, R. A., Kosar, S., Miller, O. H., Lin, Y. C., Mesgarzadeh, S., & Knight, Z. A. (2019). Sustained NPY signaling enables AgRP neurons to drive feeding. Elife, 8, e46348.

Wu, J., Zhu, C., Yang, L., Wang, Z., Wang, L., Wang, S., ... & Shu, G. (2017). N-oleoylglycine-induced hyperphagia is associated with the activation of agouti-related protein (AgRP) neuron by cannabinoid receptor type 1 (CB1R). Journal of agricultural and food chemistry, 65(5), 1051-1057.

Chen, S. R., Chen, H., Zhou, J. J., Pradhan, G., Sun, Y., Pan, H. L., & Li, D. P. (2017). Ghrelin receptors mediate ghrelin‐induced excitation of agouti‐related protein/neuropeptide Y but not pro‐opiomelanocortin neurons. Journal of neurochemistry, 142(4), 512-520.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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