AGTRAP

This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Full Name
Angiotensin II Receptor Associated Protein
Function
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
Biological Process
regulation of blood pressure Source: GO_Central
response to hypoxia
Cellular Location
Golgi apparatus membrane; Endoplasmic reticulum membrane; Cytoplasmic vesicle membrane. Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles.
Topology
Extracellular: 1-23 aa
Helical: 24-44 aa
Cytoplasmic: 45-55 aa
Helical: 56-76 aa
Extracellular: 77-86 aa
Helical: 87-107 aa
Cytoplasmic: 108-159 aa
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Anti-AGTRAP antibodies

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Mouse Anti-AGTRAP Recombinant Antibody (V2-180252) (CBMAB-A1685-YC)

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Target: AGTRAP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-180252
Application*: E, IH, WB, IP
Datasheet SDS

AGTRAP Matched Antibody Pair (032) (APMAB-032LY)

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Target: AGTRAP
Specificity: Human
Datasheet SDS

AGTRAP Matched Antibody Pair (031) (APMAB-031LY)

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Target: AGTRAP
Specificity: Human
Datasheet SDS
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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