ALDH6A1

ALDH6A1 is a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible o

Full Name

Aldehyde Dehydrogenase 6 Family Member A1

Function

Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

Biological Process

Branched-chain amino acid catabolic process Source: Reactome
Brown fat cell differentiation Source: Ensembl
Thymine catabolic process Source: BHF-UCL
Thymine metabolic process Source: UniProtKB
Valine catabolic process Source: BHF-UCL
Valine metabolic process Source: UniProtKB

Cellular Location

Mitochondrion

Involvement in disease

Methylmalonate semialdehyde dehydrogenase deficiency (MMSDHD): A metabolic disorder characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

Anti-ALDH6A1 antibodies

Mouse Anti-ALDH6A1 Recombinant Antibody (C9) (CBMAB-A2302-YC)

Datasheet

SDS

Target: ALDH6A1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: C9

Application*: E, IC, IF, IH, WB

Mouse Anti-ALDH6A1 Recombinant Antibody (6H9B7) (CBMAB-A2300-YC)

Datasheet

SDS

Target: ALDH6A1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6H9B7

Application*: WB, FC, E, IH, IF

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)