ARAF

This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2012]
Full Name
A-Raf Proto-Oncogene, Serine/Threonine Kinase
Function
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade.
Isoform 2: Serves as a positive regulator of myogenic differentiation by inducing cell cycle arrest, the expression of myogenin and other muscle-specific proteins, and myotube formation.
Biological Process
Cellular protein modification process Source: ProtInc
MAPK cascade Source: Reactome
Negative regulation of apoptotic process Source: UniProtKB
Positive regulation of peptidyl-serine phosphorylation Source: UniProtKB
Regulation of proteasomal ubiquitin-dependent protein catabolic process Source: UniProtKB
Regulation of TOR signaling Source: UniProtKB
Cellular Location
Cytosol; Mitochondrion
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Anti-ARAF antibodies

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Mouse Anti-ARAF Recombinant Antibody (3G2) (CBMAB-A0442-LY)

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Target: ARAF
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3G2
Application*: WB, E
Datasheet SDS

Mouse Anti-ARAF Recombinant Antibody (CBYC-A732) (CBMAB-A3400-YC)

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Target: ARAF
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYC-A732
Application*: E, WB
Datasheet SDS

Mouse Anti-ARAF Recombinant Antibody (6H6) (CBMAB-A3394-YC)

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Target: ARAF
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 6H6
Application*: E, WB
Datasheet SDS

Mouse Anti-ARAF Recombinant Antibody (A5) (CBMAB-A3393-YC)

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Target: ARAF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: A5
Application*: E, WB, IF, IP
Datasheet SDS

Rabbit Anti-ARAF Recombinant Antibody (EG216) (CBMAB-EN243-LY)

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Target: ARAF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG216
Application*: WB, IH
Datasheet SDS

Rabbit Anti-ARAF Recombinant Antibody (D2P9P) (CBMAB-CP2190-LY)

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Target: ARAF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: D2P9P
Application*: WB, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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