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Mouse Anti-ARAF Recombinant Antibody (3G2) (CBMAB-A0442-LY)

The product is antibody recognizes ARAF. The antibody 3G2 immunoassay techniques such as: WB, ELISA.
See all ARAF antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3G2
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
ARAF (NP_001645, 151 a.a. ~ 250 a.a) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
A-Raf Proto-Oncogene, Serine/Threonine Kinase
Entrez Gene ID
369
UniProt ID
P10398
Alternative Names
A-RAF; ARAF1; PKS2; RAFA1
Function
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade.
Isoform 2: Serves as a positive regulator of myogenic differentiation by inducing cell cycle arrest, the expression of myogenin and other muscle-specific proteins, and myotube formation.
Biological Process
Cellular protein modification process Source: ProtInc
MAPK cascade Source: Reactome
Negative regulation of apoptotic process Source: UniProtKB
Positive regulation of peptidyl-serine phosphorylation Source: UniProtKB
Regulation of proteasomal ubiquitin-dependent protein catabolic process Source: UniProtKB
Regulation of TOR signaling Source: UniProtKB
Cellular Location
Cytosol; Mitochondrion
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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