B3galt5
This gene encodes a member of a family of membrane-bound glycoproteins. The encoded protein may synthesize type 1 Lewis antigens, which are elevated in gastrointestinal and pancreatic cancers. Alternatively spliced transcript variants using multiple alternate promoters have been observed for this gene.
Full Name
Beta-1,3-Galactosyltransferase 5
Function
Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor.
Biological Process
Oligosaccharide biosynthetic process Source: Reactome
Poly-N-acetyllactosamine biosynthetic process Source: GO_Central
Protein glycosylation Source: GO_Central
Poly-N-acetyllactosamine biosynthetic process Source: GO_Central
Protein glycosylation Source: GO_Central
Cellular Location
Golgi apparatus membrane
Topology
Cytoplasmic: 1-7 aa
Helical: 8-28 aa
Lumenal: 29-310 aa
Helical: 8-28 aa
Lumenal: 29-310 aa
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Anti-B3galt5 antibodies
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Target: B3GALT5
Host: Rat
Antibody Isotype: IgM
Specificity: Human, Mouse
Clone: CBYY-0071
Application*: WB, FC, IF, IH, IP
Target: B3GALT5
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 29-310
Tag: His Tag
Target: B3GALT5
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 29-310
Tag: hFc Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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