BMP3

BMP6P1 (Bone Morphogenetic Protein 6 Pseudogene 1) is a Pseudogene.

Bone Morphogenetic Protein 3

Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification (PubMed:11138004, PubMed:15269709).
Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways (PubMed:31665064).

Cartilage development Source: UniProtKB-KW
Cell-cell signaling Source: ProtInc
Osteoblast differentiation Source: InterPro
Positive regulation of pathway-restricted SMAD protein phosphorylation Source: GO_Central
Skeletal system development Source: ProtInc
SMAD protein signal transduction Source: GO_Central

Secreted