Human BMP3 ELISA Kit (V2LY-0626-LY2620)

Name: Human BMP3 ELISA Kit
SKU: V2LY-0626-LY2620
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.005 ng/mL

Detection Range

0.01-2 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Human

Assay Type

Sandwich

Reactivity

Human

Assay Time

1.5 h

Molecule Mass

53.4 kDa

Components

Pre-coated ELISA Plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

Bone Morphogenetic Protein 3

Function

Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification (PubMed:11138004, PubMed:15269709).
Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways (PubMed:31665064).

Biological Process

Cartilage development Source: UniProtKB-KW
Cell-cell signaling Source: ProtInc
Osteoblast differentiation Source: InterPro
Positive regulation of pathway-restricted SMAD protein phosphorylation Source: GO_Central
Skeletal system development Source: ProtInc
SMAD protein signal transduction Source: GO_Central

Cellular Location

Secreted

Mathangi, R., Shyamsundar, V., & Shila, S. (2020). Immunohistochemical evaluation of bone morphogenetic protein 3 in chronic periodontitis influenced by Type2 diabetes mellitus. Drug invention today, 14(1).

TRIASWANTO, F. (2020). Distribusi Bone Morphogenetic Protein 3 (BMP3) pada Regenerat Ekor Tokek (Gekko gecko Linnaeus, 1758) (Doctoral dissertation, Universitas Gadjah Mada).

Fan, L., Fan, J., Liu, Y., Li, T., Xu, H., Yang, Y., ... & Zhao, R. C. (2018). miR-450b promotes osteogenic differentiation in vitro and enhances bone formation in vivo by targeting BMP3. Stem cells and development, 27(9), 600-611.

Agaviezor, B. O., Ajayi, F. O., & Omoyibo, T. W. (2017). Bone Morphogenetic Protein 3 (BMP3) Gene Variation in some Livestock Animals. Nigerian Journal of Biotechnology, 32, 28-32.

Houshmand, M., Abbaszadegan, M. R., & Kerachian, M. A. (2017). Assessment of bone morphogenetic protein 3 methylation in Iranian patients with colorectal cancer. Middle East journal of digestive diseases, 9(3), 158.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Bmp3 ELISA Kit (CAT#: V2LY-0626-LY1146)

Related Products

Mouse Anti-BMP3 Recombinant Antibody (CBLNB-130) (CAT#: CBMAB-1216-CN)

Mouse Anti-BMP3 Monoclonal Antibody (203706) (CAT#: CBMAB-0946-YC)

Mouse Bmp3 ELISA Kit (CAT#: V2LY-0626-LY1146)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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