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CAND2

CAND2 (Cullin Associated And Neddylation Dissociated 2 (Putative)) is a Protein Coding gene. Diseases associated with CAND2 include Esophageal Atresia/Tracheoesophageal Fistula. Gene Ontology (GO) annotations related to this gene include binding and TBP-class protein binding. An important paralog of this gene is CAND1.
Full Name
cullin-associated and neddylation-dissociated 2 (putative)
Function
Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes.
Biological Process
Positive regulation of transcription, DNA-templated Source: UniProtKB
Protein ubiquitination Source: GO_Central
SCF complex assembly Source: GO_Central
Cellular Location
Nucleus
PTM
Ubiquitinated and targeted for proteasomal degradation.
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Anti-CAND2 antibodies

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Mouse Anti-CAND2 Recombinant Antibody (CBYJT-1058) (CBMAB-T0068-YJ)

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Target: CAND2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat, Mouse
Clone: CBYJT-1058
Application*: WB, IP, IF, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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