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CAND2

CAND2 (Cullin Associated And Neddylation Dissociated 2 (Putative)) is a Protein Coding gene. Diseases associated with CAND2 include Esophageal Atresia/Tracheoesophageal Fistula. Gene Ontology (GO) annotations related to this gene include binding and TBP-class protein binding. An important paralog of this gene is CAND1.

Full Name

cullin-associated and neddylation-dissociated 2 (putative)

Function

Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes.

Biological Process

Positive regulation of transcription, DNA-templated Source: UniProtKB
Protein ubiquitination Source: GO_Central
SCF complex assembly Source: GO_Central

Cellular Location

Nucleus

PTM

Ubiquitinated and targeted for proteasomal degradation.

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Anti-CAND2 antibodies

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Mouse Anti-CAND2 Recombinant Antibody (CBYJT-1058) (CBMAB-T0068-YJ)

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Target: CAND2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Rat, Mouse

Clone: CBYJT-1058

Application*: WB, IP, IF, E

Mouse Anti-CAND2 Recombinant Antibody (CBYJT-1058)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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