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CARNMT1

The protein encoded by this gene is a methyltransferase that converts carnosine to anserine, a dipeptide found abundantly in skeletal muscle. The encoded protein can methylate other dipeptides as well. Three transcript variants encoding two different isoforms have been found for this gene.
Full Name
Carnosine N-Methyltransferase 1
Function
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
Biological Process
Carnosine metabolic process Source: UniProtKB
Histidine catabolic process Source: Reactome
Methylation Source: UniProtKB-KW
Cellular Location
Nucleus; Cytosol

Anti-CARNMT1 antibodies

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Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0952
Application*: F, IF, IH
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1E8
Application*: C, IC/IF, WB
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4A2
Application*: C, WB
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4B7
Application*: WB, F, IH, IC/IF, P
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6 E4
Application*: F, IF, IH
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6A2
Application*: WB
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6E4
Application*: F, IC/IF, IH, P, WB
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0818
Application*: F, IF, WB
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-3004
Application*: WB, IH, IF, F
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Rat, Monkey
Clone: CBXC-2211
Application*: WB, F
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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