CARNMT1
The protein encoded by this gene is a methyltransferase that converts carnosine to anserine, a dipeptide found abundantly in skeletal muscle. The encoded protein can methylate other dipeptides as well. Three transcript variants encoding two different isoforms have been found for this gene.
Full Name
Carnosine N-Methyltransferase 1
Function
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
Biological Process
Carnosine metabolic process Source: UniProtKB
Histidine catabolic process Source: Reactome
Methylation Source: UniProtKB-KW
Histidine catabolic process Source: Reactome
Methylation Source: UniProtKB-KW
Cellular Location
Nucleus; Cytosol
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Anti-CARNMT1 antibodies
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Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6A2
Application*: WB
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6E4
Application*: WB, F, IH, IC/IF
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4B7
Application*: WB, F, IH, IC/IF
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Monkey, Dog
Clone: 4A2
Application*: F, WB
Target: CARNMT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1E8
Application*: F, IC/IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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