CCL16

CCL16 (C-C Motif Chemokine Ligand 16) is a Protein Coding gene. Diseases associated with CCL16 include Corneal Dystrophy, Lisch Epithelial and Visceral Leishmaniasis. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include chemokine activity and chemoattractant activity. An important paralog of this gene is CCL14.
Full Name
C-C Motif Chemokine Ligand 16
Function
Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
Biological Process
Cell-cell signaling Source: ProtInc
Cell communication Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Cellular Location
Secreted
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Anti-CCL16 antibodies

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Mouse Anti-CCL16 Recombinant Antibody (70218) (CBMAB-C8402-LY)

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Target: CCL16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 70218
Application*: E, N
Functional Assay
Datasheet SDS

Rabbit Anti-CCL16 Recombinant Antibody (13) (CBMAB-C2692-LY)

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Target: CCL16
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 13
Application*: E
Datasheet SDS

Mouse Anti-CCL16 Recombinant Antibody (01) (CBMAB-C1562-LY)

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Target: CCL16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 01
Application*: E
Datasheet SDS

Mouse Anti-CCL16 Recombinant Antibody (CBYCL-108) (CBMAB-L0009-YC)

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Target: CCL16
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYCL-108
Application*: WB, E, I
Functional Assay
Datasheet SDS

Mouse Anti-CCL16 Recombinant Antibody (CBYCL-107) (CBMAB-L0008-YC)

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Target: CCL16
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-107
Application*: E
Datasheet SDS

Mouse Anti-CCL16 Recombinant Antibody (CBYJL-1010) (CBMAB-L0419-YJ)

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Target: CCL16
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1010
Application*: E
Datasheet SDS

Mouse Anti-CCL16 Recombinant Antibody (M912275) (CBMAB-L0418-YJ)

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Target: CCL16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: M912275
Application*: E, WB
Datasheet SDS

Mouse Anti-CCL16 Recombinant Antibody (CBYJL-1008) (CBMAB-L0415-YJ)

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Target: CCL16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1008
Application*: E
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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