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CCL16

CCL16 (C-C Motif Chemokine Ligand 16) is a Protein Coding gene. Diseases associated with CCL16 include Corneal Dystrophy, Lisch Epithelial and Visceral Leishmaniasis. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include chemokine activity and chemoattractant activity. An important paralog of this gene is CCL14.

Full Name

C-C Motif Chemokine Ligand 16

Function

Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.

Biological Process

Cell-cell signaling Source: ProtInc
Cell communication Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central

Cellular Location

Secreted

Anti-CCL16 antibodies

Mouse Anti-CCL16 Recombinant Antibody (CBXC-0111) (CBMAB-C3680-CQ)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXC-0111

Application*: E

Mouse Anti-CCL16 Recombinant Antibody (CBXC-1293) (CBMAB-C1560-CQ)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-1293

Application*: IS

Mouse Anti-CCL16 Recombinant Antibody (CBYY-C1062) (CBMAB-C2499-YY)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-C1062

Application*: IH, N, WB

Rabbit Anti-CCL16 Recombinant Antibody (CBFYC-0938) (CBMAB-C0994-FY)

SDS

Target: CCL16

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYC-0938

Application*: E

Mouse Anti-CCL16 Recombinant Antibody (CBFYC-0937) (CBMAB-C0993-FY)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-0937

Application*: E

Mouse Anti-CCL16 Recombinant Antibody (CBFYC-0936) (CBMAB-C0992-FY)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-0936

Application*: IH, N, WB

Mouse Anti-CCL16 Recombinant Antibody (CBFYC-0935) (CBMAB-C0991-FY)

SDS

Target: CCL16

Host: Mouse

Specificity: Human

Clone: CBFYC-0935

Application*: E, WB

Mouse Anti-CCL16 Recombinant Antibody (CBFYH-3387) (CBMAB-H3931-FY)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYH-3387

Application*: E, FN

Mouse Anti-CCL16 Recombinant Antibody (CBYJL-1010) (CBMAB-L0419-YJ)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJL-1010

Application*: WB, P, N

Mouse Anti-CCL16 Recombinant Antibody (M912275) (CBMAB-L0418-YJ)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: M912275

Application*: E, CT, WB

Mouse Anti-CCL16 Recombinant Antibody (CBYJL-1008) (CBMAB-L0415-YJ)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJL-1008

Application*: E

Mouse Anti-CCL16 Recombinant Antibody (LEC67) (CBMAB-AP863LY)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: LEC67

Application*: ELISA, FA

Mouse Anti-CCL16 Recombinant Antibody (LEC66) (CBMAB-AP862LY)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: LEC66

Application*: ELISA, FA

Mouse Anti-CCL16 Recombinant Antibody (MM0140-3J10) (CBMAB-C9801-LY)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: MM0140-3J10

Application*: WB, IH, P, B/N

Mouse Anti-CCL16 Recombinant Antibody (70218) (CBMAB-C8402-LY)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 70218

Application*: WB, IH, N, IS, MC, EC

Rabbit Anti-CCL16 Recombinant Antibody (13) (CBMAB-C2692-LY)

SDS

Target: CCL16

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 13

Application*: E

Mouse Anti-CCL16 Recombinant Antibody (01) (CBMAB-C1562-LY)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 01

Application*: E

Mouse Anti-CCL16 Recombinant Antibody (CBYCL-108) (CBMAB-L0009-YC)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYCL-108

Application*: WB, E, IH

Mouse Anti-CCL16 Recombinant Antibody (CBYCL-107) (CBMAB-L0008-YC)

SDS

Target: CCL16

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYCL-107

Application*: WB, P, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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