CD109

CD109 (CD109 Molecule) is a Protein Coding gene. Diseases associated with CD109 include Fetal And Neonatal Alloimmune Thrombocytopenia and Vulva Squamous Cell Carcinoma. Among its related pathways are Metabolism of proteins and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity and transforming growth factor beta binding. An important paralog of this gene is CPAMD8.
Full Name
CD109 Molecule
Function
Modulates negatively TGFB1 signaling in keratinocytes.
Biological Process
Hair follicle development Source: Ensembl
Negative regulation of keratinocyte proliferation Source: Ensembl
Negative regulation of protein phosphorylation Source: Ensembl
Negative regulation of transforming growth factor beta receptor signaling pathway Source: UniProtKB
Negative regulation of wound healing Source: UniProtKB
Osteoclast fusion Source: Ensembl
Platelet degranulation Source: Reactome
Regulation of keratinocyte differentiation Source: Ensembl
Cellular Location
Cell membrane
PTM
N-glycosylated.
2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form.
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Anti-CD109 antibodies

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Rabbit Anti-CD109 Recombinant Antibody (CBXC-1827) (CBMAB-C5460-CQ)

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Target: CD109
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-1827
Application*: WB
Datasheet SDS

Mouse Anti-CD109 Recombinant Antibody (CBT4171) (V2LY-0625-LY1693)

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Target: CD109
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4171
Application*: IH, IC, F
Datasheet SDS

Mouse Anti-CD109 Recombinant Antibody (CBT4639) (V2LY-0625-LY1692)

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Target: CD109
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4639
Application*: IC, F
Datasheet SDS

Mouse Anti-CD109 Recombinant Antibody (CBT3916) (V2LY-0625-LY1057)

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Target: CD109
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3916
Application*: F
Datasheet SDS

Mouse Anti-CD109 Recombinant Antibody (AP930) (CBMAB-AP930LY)

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Target: CD109
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: AP930
Application*: F
Datasheet SDS

Mouse Anti-CD109 Recombinant Antibody (W7C5) (CBMAB-C9972-LY)

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Target: CD109
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: W7C5
Application*: F
Datasheet SDS

Mouse Anti-CD109 Recombinant Antibody (CBCNC-158) (CBMAB-C1514-CN)

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Target: CD109
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNC-158
Application*: WB, IC, P, F, E
Datasheet SDS

Mouse Anti-CD109 Recombinant Antibody (CBXC-2777) (CBMAB-C5459-CQ)

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Target: CD109
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-2777
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CD109 Recombinant Antibody (CBFYC-1101) (CBMAB-C1158-FY)

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Target: CD109
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-1101
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-CD109 Recombinant Antibody (CBFYC-1100) (CBMAB-C1157-FY)

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Target: CD109
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-1100
Application*: WB, IP, IF, E
Datasheet SDS

Rabbit Anti-CD109 Recombinant Antibody (C7140) (CBMAB-C7140-LY)

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Target: CD109
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: C7140
Application*: WB
Datasheet SDS

Mouse Anti-CD109 Recombinant Antibody (496920) (CBMAB-C1362-LY)

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Target: CD109
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 496920
Application*: F, IH
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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