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CD93

The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq]
Full Name
CD93 molecule
Function
Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
Biological Process
Cell-cell adhesion Source: UniProtKB
Macrophage activation Source: UniProtKB
Neutrophil degranulation Source: Reactome
Phagocytosis Source: UniProtKB
Viral process Source: UniProtKB-KW
Cellular Location
Membrane
Topology
Extracellular: 24-580
Helical: 581-601
Cytoplasmic: 602-652
PTM
N- and O-glycosylated.

Anti-CD93 antibodies

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Target: CD93
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-1528
Application*: E, WB
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: mNI-11
Application*: F, IH, IP
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1056
Application*: F
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2756
Application*: WB, E, IH
Target: CD93
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBXC-1023
Application*: F, IC, MC
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: VIMD2
Application*: F
Target: CD93
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: R139
Application*: WB, F, E, IP
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1498
Application*: E
Target: CD93
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-1497
Application*: E
Target: CD93
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat
Clone: CBFYC-1496
Application*: E
Target: CD93
Host: Mouse
Antibody Isotype: IgG3, λ
Specificity: Human
Clone: CBFYC-1494
Application*: E, WB
Target: CD93
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-0106
Application*: F
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0091
Application*: F
Target: CD93
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYC-0090
Application*: F
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A10E10
Application*: WB, F, E, IH, IF, P
Target: CD93
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat
Clone: 164
Application*: E
Target: CD93
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 223437
Application*: F, IC, MC
Target: CD93
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: R3
Application*: F
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: X-2
Application*: IH, FC
Target: CD93
Host: Mouse
Antibody Isotype: IgG3, λ
Specificity: Human
Clone: CBYY-C1656
Application*: E, WB
Target: CD93
Host: Mouse
Antibody Isotype: IgG3, λ
Specificity: Human
Clone: 3D12
Application*: E, WB
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2F7D11
Application*: E, WB, P, IF/C, F
Target: CD93
Host: Mouse
Antibody Isotype: IgG3, λ
Specificity: Human
Clone: 1A4
Application*: E, WB
Target: CD93
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 14i108
Application*: E, F, IC, C, WB
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1.T.23
Application*: WB, F, IC/IF
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 02
Application*: E
Target: CD93
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 004
Application*: E
Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 273107
Application*: WB, F, MC
Target: CD93
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 01
Application*: F
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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