CD93

The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq]
Full Name
CD93 molecule
Function
Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
Biological Process
Cell-cell adhesion Source: UniProtKB
Macrophage activation Source: UniProtKB
Neutrophil degranulation Source: Reactome
Phagocytosis Source: UniProtKB
Viral process Source: UniProtKB-KW
Cellular Location
Membrane
Topology
Extracellular: 24-580
Helical: 581-601
Cytoplasmic: 602-652
PTM
N- and O-glycosylated.
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Anti-CD93 antibodies

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Rabbit Anti-CD93 Recombinant Antibody (164) (CBMAB-C3324-LY)

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Target: CD93
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat
Clone: 164
Application*: E
Datasheet SDS

Human Anti-CD93 Recombinant Antibody (
15B9) (V2LY-0725-LY1417)

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Target: CD93
Host: Human
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 15B9
Application*: E, F
Datasheet SDS

Mouse Anti-CD93 Recombinant Antibody (CBT2480) (V2LY-0625-LY39)

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Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2480
Application*: IH
Datasheet SDS

Mouse Anti-CD93 Recombinant Antibody (CBT4768) (V2LY-0625-LY38)

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Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4768
Application*: IH, IC, F
Datasheet SDS

Rabbit Anti-CD93 Recombinant Antibody (CBFYC-1496) (CBMAB-C1555-FY)

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Target: CD93
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat
Clone: CBFYC-1496
Application*: F
Datasheet SDS

Human Anti-CD93 Recombinant Antibody (CBFYC-0106) (CBMAB-C0123-FY)

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Target: CD93
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0106
Application*: E, F
Datasheet SDS

Mouse Anti-CD93 Recombinant Antibody (CBFYC-0091) (CBMAB-C0105-FY)

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Target: CD93
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBFYC-0091
Application*: WB, IF, E, IP
Datasheet SDS

Rat Anti-CD93 Recombinant Antibody (CBFYC-0090) (CBMAB-C0104-FY)

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Target: CD93
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYC-0090
Application*: F, IF
Datasheet SDS

Mouse Anti-CD93 Recombinant Antibody (3D12) (CBMAB-C5859-LY)

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Target: CD93
Host: Mouse
Antibody Isotype: IgG3, λ
Specificity: Human
Clone: 3D12
Application*: E, WB
Datasheet SDS

Mouse Anti-CD93 Recombinant Antibody (1A4) (CBMAB-C3542-LY)

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Target: CD93
Host: Mouse
Antibody Isotype: IgG3, λ
Specificity: Human
Clone: 1A4
Application*: E, WB
Datasheet SDS

Mouse Anti-CD93 Recombinant Antibody (2) (CBMAB-C1659-LY)

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Target: CD93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2
Application*: E
Datasheet SDS

Rabbit Anti-CD93 Recombinant Antibody (4) (CBMAB-C1509-LY)

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Target: CD93
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 4
Application*: E
Datasheet SDS

Mouse Anti-CD93 Recombinant Antibody (1) (CBMAB-C0035-LY)

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Target: CD93
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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