CDC42SE2
CDC42SE2 (CDC42 Small Effector 2) is a Protein Coding gene. Diseases associated with CDC42SE2 include Schizophrenia. Gene Ontology (GO) annotations related to this gene include structural molecule activity. An important paralog of this gene is CDC42SE1.
Full Name
CDC42 Small Effector 2
Function
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
Biological Process
Phagocytosis Source: UniProtKB-KW
Regulation of cell shape Source: UniProtKB-KW
Regulation of Rho protein signal transduction Source: InterPro
Regulation of signal transduction Source: UniProtKB
Regulation of cell shape Source: UniProtKB-KW
Regulation of Rho protein signal transduction Source: InterPro
Regulation of signal transduction Source: UniProtKB
Cellular Location
Cytoskeleton; Cell membrane; Phagocytic cup. Recruited to the activated TCR prior actin polymerization. Localizes at the phagocytic cup of macrophages.
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Anti-CDC42SE2 antibodies
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Target: CDC42SE2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBXC-1918
Application*: WB, IH
Target: CDC42SE2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBFYC-1522
Application*: WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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