Mouse Anti-CDC42SE2 Recombinant Antibody (CBXC-1918) (CBMAB-C5792-CQ)

Name: Mouse Anti-CDC42SE2 Recombinant Antibody (CBXC-1918)
SKU: CBMAB-C5792-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXC-1918

Application

WB, IHC

Immunogen

Full-length human recombinant protein of human CDC42SE2 produced in E. coli

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:2,000
IHC	1:150

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

CDC42 Small Effector 2

Introduction

CDC42SE2 (CDC42 Small Effector 2) is a Protein Coding gene. Diseases associated with CDC42SE2 include Schizophrenia. Gene Ontology (GO) annotations related to this gene include structural molecule activity. An important paralog of this gene is CDC42SE1.

Entrez Gene ID

56990

UniProt ID

Q9NRR3

Alternative Names

CDC42 Small Effector 2; Small Effector Of CDC42 Protein 2; SPEC2; Non-Kinase Cdc42 Effector Protein SPEC2; CDC42 Small Effector Protein 2;

Function

Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.

Biological Process

Phagocytosis Source: UniProtKB-KW
Regulation of cell shape Source: UniProtKB-KW
Regulation of Rho protein signal transduction Source: InterPro
Regulation of signal transduction Source: UniProtKB

Cellular Location

Cytoskeleton; Cell membrane; Phagocytic cup. Recruited to the activated TCR prior actin polymerization. Localizes at the phagocytic cup of macrophages.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-CDC42SE2 Recombinant Antibody (CBFYC-1522) (CAT#: CBMAB-C1581-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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