CDH26

CDH26 (Cadherin 26) is a Protein Coding gene. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH2.

Full Name

Cadherin 26

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Ligand for integrins alpha-E/beta-7, ITGAE:ITGAB7, alpha-4/beta-7, ITGA4:ITGAB7 and alpha-4/beta-1, ITGA4:ITGAB1 through which modulates CD4+ T cells activation (PubMed:28051089).

Biological Process

CD4-positive, alpha-beta T cell activation Source: UniProtKB
Cell-cell adhesion via plasma-membrane adhesion molecules Source: GO_Central
Homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro

Cellular Location

Cell membrane

Topology

Extracellular: 28-614
Helical: 615-635
Cytoplasmic: 636-832

PTM

N-glycosylated.

Anti-CDH26 antibodies

Mouse Anti-CDH26 Recombinant Antibody (6C10) (CBMAB-C8113-LY)

Datasheet

SDS

Target: CDH26

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 6C10

Application*: E, WB

Rabbit Anti-CDH26 Recombinant Antibody (EG592) (CBMAB-EN714-LY)

Datasheet

SDS

Target: CDH26

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG592

Application*: IF: 1:100~1:500 ELISA: 1:1000

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)