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Mouse Anti-CDH26 Recombinant Antibody (6C10) (CBMAB-C8113-LY)

This product is antibody recognizes CDH26. The antibody 6C10 immunoassay techniques such as: ELISA, WB.
See all CDH26 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
6C10
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
CDH26 (NP_068582.2, 1 a.a. ~ 165 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: MKPLIWTWSD VEGQRPALLI CTAAAGPTQG VKDLEEVPPS AASQSAQARC ALGSWGYGKP FEPRSVKNIH STPAYPDATM HRQLLAPVEG RMAETLNQKL HVANVLE
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cadherin 26
Introduction
CDH26 (Cadherin 26) is a Protein Coding gene. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH2.
Entrez Gene ID
60437
UniProt ID
Q8IXH8
Alternative Names
Cadherin 26; Cadherin-Like Protein VR20; Cadherin-Like 26; Cadherin-Like Protein 26; VR20;
Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Ligand for integrins alpha-E/beta-7, ITGAE:ITGAB7, alpha-4/beta-7, ITGA4:ITGAB7 and alpha-4/beta-1, ITGA4:ITGAB1 through which modulates CD4+ T cells activation (PubMed:28051089).
Biological Process
CD4-positive, alpha-beta T cell activation Source: UniProtKB
Cell-cell adhesion via plasma-membrane adhesion molecules Source: GO_Central
Homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
Cellular Location
Cell membrane
Topology
Extracellular: 28-614
Helical: 615-635
Cytoplasmic: 636-832
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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