CGGBP1
CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.[supplied by OMIM
Full Name
CGG triplet repeat binding protein 1
Function
Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter.
Biological Process
Negative regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of gene expression Source: GO_Central
Regulation of gene expression, epigenetic Source: ARUK-UCL
Regulation of gene expression Source: GO_Central
Regulation of gene expression, epigenetic Source: ARUK-UCL
Cellular Location
Nucleus
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Anti-CGGBP1 antibodies
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Target: CGGBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 1D11
Application*: WB, IH, IF, E
Target: CGGBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Horse, Cattle, Dog
Clone: CBXC-0406
Application*: E, IF, IP, WB
Target: CGGBP1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human, Mouse, Rat, Pig
Clone: CBFYC-1790
Application*: E, IF, IP, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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