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CITED4

CITED4 belongs to a family of transcriptional coactivators that bind several proteins, including CREB-binding protein (MIM 600140) and p300 (MIM 602700).[supplied by OMIM

Full Name

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

Function

Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells.

Biological Process

Positive regulation of transcription by RNA polymerase II Source: Reactome
Response to estrogen Source: UniProtKB

Cellular Location

Nucleus; Cytoplasm

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Anti-CITED4 antibodies

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Mouse Anti-CITED4 Recombinant Antibody (HT13-2D6.3) (CBMAB-C0722-CQ)

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Target: CITED4

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: HT13-2D6.3

Application*: WB, F, E, IF, P

Mouse Anti-CITED4 Recombinant Antibody (4F6) (CBMAB-C6945-LY)

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Target: CITED4

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4F6

Application*: E, IH, WB, IF

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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