CNTF
CNTF (Ciliary Neurotrophic Factor) is a Protein Coding gene. Diseases associated with CNTF include Motor Neuron Disease and Epilepsy, Familial Temporal Lobe, 2. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. Gene Ontology (GO) annotations related to this gene include growth factor activity and ciliary neurotrophic factor receptor binding.
Full Name
Ciliary Neurotrophic Factor
Function
CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Biological Process
Astrocyte activation Source: GO_Central
Ciliary neurotrophic factor-mediated signaling pathway Source: BHF-UCL
Cytokine-mediated signaling pathway Source: Reactome
Muscle organ morphogenesis Source: Ensembl
Negative regulation of neuron apoptotic process Source: BHF-UCL
Negative regulation of photoreceptor cell differentiation Source: Ensembl
Neuron development Source: Ensembl
Positive regulation of axon regeneration Source: GO_Central
Positive regulation of cell population proliferation Source: GO_Central
Positive regulation of gene expression Source: MGI
Positive regulation of tyrosine phosphorylation of STAT protein Source: BHF-UCL
Regulation of retinal cell programmed cell death Source: Ensembl
Signal transduction Source: ProtInc
Ciliary neurotrophic factor-mediated signaling pathway Source: BHF-UCL
Cytokine-mediated signaling pathway Source: Reactome
Muscle organ morphogenesis Source: Ensembl
Negative regulation of neuron apoptotic process Source: BHF-UCL
Negative regulation of photoreceptor cell differentiation Source: Ensembl
Neuron development Source: Ensembl
Positive regulation of axon regeneration Source: GO_Central
Positive regulation of cell population proliferation Source: GO_Central
Positive regulation of gene expression Source: MGI
Positive regulation of tyrosine phosphorylation of STAT protein Source: BHF-UCL
Regulation of retinal cell programmed cell death Source: Ensembl
Signal transduction Source: ProtInc
Cellular Location
Cytoplasm
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Anti-CNTF antibodies
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Target: CNTF
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: C11081
Application*: WB, N
Target: CNTF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: CBCNC-038
Application*: WB
Target: CNTF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C4008
Application*: E, IP, WB
Target: CNTF
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-1019
Application*: WB, N, E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG3
Specificity: Rat
Clone: CBYY-C2958
Application*: E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2956
Application*: E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-C0033
Application*: WB, IP, IF, E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0032
Application*: WB, IP, IF, E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-2012
Application*: WB, IP, IF, E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYC-2009
Application*: WB, IP, IF, E, P
Target: CNTF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-2008
Application*: WB, IP, IF, E
Target: CNTF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 121
Application*: E
Target: CNTF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 1
Application*: E
Target: CNTF
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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