CNTF Matched Antibody Pair (283) (APMAB-283LY)

Name: CNTF Matched Antibody Pair (283)
SKU: APMAB-283LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-CNTF polyclonal antibody, 100 ug

Detection Antibody

Anti-CNTF Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

CNTF (Ciliary Neurotrophic Factor) is a Protein Coding gene. Diseases associated with CNTF include Motor Neuron Disease and Epilepsy, Familial Temporal Lobe, 2. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. Gene Ontology (GO) annotations related to this gene include growth factor activity and ciliary neurotrophic factor receptor binding.

Alternative Names

Ciliary Neurotrophic Factor; HCNTF;

Entrez Gene ID

1270

UniProt ID

P26441

More Infomation

Wang, Y., Rhee, K. D., Pellegrini, M., & Yang, X. J. (2020). Impacts of ciliary neurotrophic factor on the retinal transcriptome in a mouse model of photoreceptor degeneration. Scientific reports, 10(1), 1-11.

Chew, E. Y., Clemons, T. E., Jaffe, G. J., Johnson, C. A., Farsiu, S., Lad, E. M., ... & Phase 2 CNTF Research Group. (2019). Effect of ciliary neurotrophic factor on retinal neurodegeneration in patients with macular telangiectasia type 2: a randomized clinical trial. Ophthalmology, 126(4), 540-549.

Jia, C., Brown, R. W., Malone, H. M., Burgess, K. C., Gill, W. D., Keasey, M. P., & Hagg, T. (2019). Ciliary neurotrophic factor is a key sex-specific regulator of depressive-like behavior in mice. Psychoneuroendocrinology, 100, 96-105.

Ghasemi, M., Alizadeh, E., Saei Arezoumand, K., Fallahi Motlagh, B., & Zarghami, N. (2018). Ciliary neurotrophic factor (CNTF) delivery to retina: an overview of current research advancements. Artificial cells, nanomedicine, and biotechnology, 46(8), 1694-1707.

Li, S., Sato, K., Gordon, W. C., Sendtner, M., Bazan, N. G., & Jin, M. (2018). Ciliary neurotrophic factor (CNTF) protects retinal cone and rod photoreceptors by suppressing excessive formation of the visual pigments. Journal of Biological Chemistry, 293(39), 15256-15268.

Zheng, K., Zhang, Q., Sheng, Z., Li, Y., & Lu, H. H. (2018). Ciliary neurotrophic factor (CNTF) protects myocardial cells from oxygen glucose deprivation (OGD)/re-oxygenation via activation of Akt-Nrf2 signaling. Cellular Physiology and Biochemistry, 51(4), 1852-1862.

Baek, J. Y., Jeong, J. Y., Kim, K. I., Won, S. Y., Chung, Y. C., Nam, J. H., ... & Jin, B. K. (2018). Inhibition of microglia-derived oxidative stress by ciliary neurotrophic factor protects dopamine neurons in vivo from MPP+ neurotoxicity. International journal of molecular sciences, 19(11), 3543.

Ma, M., Xu, Y., Xiong, S., Zhang, J., Gu, Q., Ke, B., & Xu, X. (2018). Involvement of ciliary neurotrophic factor in early diabetic retinal neuropathy in streptozotocin-induced diabetic rats. Eye, 32(9), 1463-1471.

Shpak, A. A., Guekht, A. B., Druzhkova, T. A., Kozlova, K. I., & Gulyaeva, N. V. (2017). Ciliary neurotrophic factor in patients with primary open-angle glaucoma and age-related cataract. Molecular vision, 23, 799.

Fan, L., Xiong, Y., Fu, Z., Xu, D., Wang, L., Chen, Y., ... & Ye, Q. (2017). Polyaniline promotes peripheral nerve regeneration by enhancement of the brain‑derived neurotrophic factor and ciliary neurotrophic factor expression and activation of the ERK1/2/MAPK signaling pathway. Molecular medicine reports, 16(5), 7534-7540.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant CNTF protein, His Tag (CAT#: V2LY-0526-LY3303)

Human Recombinant CNTFR protein, His Tag (CAT#: V2LY-0526-LY3304)

Mouse Recombinant CNTF protein, His Tag (CAT#: V2LY-0526-LY8140)

Rat Recombinant CNTF protein (CAT#: V2LY-0526-LY9301)

Human CNTF ELISA Kit (CAT#: V2LY-0626-LY1478)

Mouse Cntf ELISA Kit (CAT#: V2LY-0626-LY725)

Rat Cntf ELISA Kit (CAT#: V2LY-0626-LY788)

Related Products

Mouse Anti-CNTF Recombinant Antibody (CBYY-C2956) (CAT#: V2LY-1206-LY517)

Mouse Anti-CNTF Recombinant Antibody (CBXC-1019) (CAT#: V2LY-1206-LY519)

Mouse Anti-CNTF Recombinant Antibody (CBYY-C2958) (CAT#: V2LY-1206-LY518)

Mouse Anti-CNTF Recombinant Antibody (CBFYC-2012) (CAT#: V2LY-1206-LY514)

Rat Recombinant CNTF protein (CAT#: V2LY-0526-LY9301)

Mouse Recombinant CNTF protein, His Tag (CAT#: V2LY-0526-LY8140)

Mouse Anti-CNTF Recombinant Antibody (CBFYC-2009) (CAT#: V2LY-1206-LY513)

Mouse Anti-CNTF Recombinant Antibody (CBYY-C0032) (CAT#: V2LY-1206-LY515)

Mouse Anti-CNTF Recombinant Antibody (CBYY-C0033) (CAT#: V2LY-1206-LY516)

Rat Cntf ELISA Kit (CAT#: V2LY-0626-LY788)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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