CXCL14
CXCL14 (C-X-C Motif Chemokine Ligand 14) is a Protein Coding gene. Diseases associated with CXCL14 include Squamous Cell Carcinoma, Head And Neck and Pelvic Lipomatosis. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include chemokine activity.
Full Name
C-X-C Motif Chemokine Ligand 14
Function
Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell-cell signaling Source: ProtInc
Chemotaxis Source: ProtInc
Inner ear development Source: Ensembl
Killing of cells of other organism Source: UniProtKB
Negative regulation of myoblast differentiation Source: Ensembl
Positive regulation of natural killer cell chemotaxis Source: Ensembl
Signal transduction Source: ProtInc
Cell-cell signaling Source: ProtInc
Chemotaxis Source: ProtInc
Inner ear development Source: Ensembl
Killing of cells of other organism Source: UniProtKB
Negative regulation of myoblast differentiation Source: Ensembl
Positive regulation of natural killer cell chemotaxis Source: Ensembl
Signal transduction Source: ProtInc
Cellular Location
Secreted
PTM
Ubiquitinated, followed by degradation by the proteasome.
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Anti-CXCL14 antibodies
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Target: CXCL14
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: C3436
Application*: WB, IH
Target: CXCL14
Sensitivity: 0.024 ng/mL
Detection Range: 0.05-30 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Cxcl14
Sensitivity: 0.057 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: CXCL14
Expressed Host: E. coli
Sequence: Amino Acid: 23-99
Target: CXCL14
Expressed Host: E. coli
Sequence: Amino Acid: 35-111
Tag: His Tag
Target: CXCL14
Expressed Host: E. coli
Sequence: Amino Acid: 35-111
Target: CXCL14
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBXC-0970
Application*: E, WB, P
Target: CXCL14
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXC-1494
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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