Mouse Cxcl14 ELISA Kit (V2LY-0626-LY2246)

Name: Mouse Cxcl14 ELISA Kit
SKU: V2LY-0626-LY2246
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.057 ng/mL

Detection Range

0.1-40 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Mouse

Assay Type

Sandwich

Reactivity

Mouse

Assay Time

1.5 h

Molecule Mass

11.7 kDa

Components

Pre-coated ELISA plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

C-X-C Motif Chemokine Ligand 14

Function

Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.

Biological Process

Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell-cell signaling Source: ProtInc
Chemotaxis Source: ProtInc
Inner ear development Source: Ensembl
Killing of cells of other organism Source: UniProtKB
Negative regulation of myoblast differentiation Source: Ensembl
Positive regulation of natural killer cell chemotaxis Source: Ensembl
Signal transduction Source: ProtInc

Cellular Location

Secreted

PTM

Ubiquitinated, followed by degradation by the proteasome.

Chen, L., Lei, Y., & Zhang, L. (2021). Role of CXC motif chemokine ligand 14 promoter region DNA methylation and single nucleotide polymorphism in influenza A severity. Respiratory Medicine, 185, 106462.

Matsushita, Y., Hasegawa, Y., Takebe, N., Onodera, K., Shozushima, M., Oda, T., ... & Ishigaki, Y. (2021). Serum C‐X‐C motif chemokine ligand 14 levels are associated with serum C‐peptide and fatty liver index in type 2 diabetes mellitus patients. Journal of Diabetes Investigation, 12(6), 1042-1049.

Wang, C., Zhao, N., Sato, F., Tanimoto, K., Okada, H., Liu, Y., & Bhawal, U. K. (2021). The roles of Y-box-binding protein (YB)-1 and CXC motif chemokine ligand 14 (CXCL14) in the progression of prostate cancer via extracellular-signal-regulated kinase (ERK) signaling. Bioengineered, 12(2), 9128-9139.

Cereijo, R., Quesada-Lopez, T., Gavalda-Navarro, A., Tarascó, J., Pellitero, S., Reyes, M., ... & Villarroya, F. (2021). The chemokine CXCL14 is negatively associated with obesity and concomitant type-2 diabetes in humans. International Journal of Obesity, 45(3), 706-710.

Qi, J., Li, J., Wang, Y., Wang, W., Zhu, Q., He, Y., ... & Sun, Y. (2021). Novel role of CXCL14 in modulating STAR expression in luteinized granulosa cells: implication for progesterone synthesis in PCOS patients. Translational Research, 230, 55-67.

García-Beltran, C., Cereijo, R., Quesada-López, T., Malpique, R., López-Bermejo, A., de Zegher, F., ... & Villarroya, F. (2020). Reduced circulating levels of chemokine CXCL14 in adolescent girls with polycystic ovary syndrome: normalization after insulin sensitization. BMJ Open Diabetes Research and Care, 8(1), e001035.

Ko, H. M., Moon, J. S., Shim, H. K., Lee, S. Y., Kang, J. H., Kim, M. S., ... & Kim, S. H. (2020). Inhibitory effect of CXC motif chemokine ligand 14 on the osteogenic differentiation of human periodontal ligament cells through transforming growth factor-beta1. Archives of Oral Biology, 115, 104733.

Yang, X. Y., Ozawa, S., Kato, Y., Maehata, Y., Izukuri, K., Ikoma, T., ... & Hata, R. I. (2019). CXC motif chemokine ligand 14 is a unique multifunctional regulator of tumor progression. International Journal of Molecular Sciences, 20(8), 1872.

Li, L., Li, Q., Wei, L., Wang, Z., Ma, W., Liu, F., ... & Qian, Y. (2019). Chemokine (C‐X‐C motif) ligand 14 contributes to lipopolysaccharide‐induced fibrogenesis in mouse L929 fibroblasts via modulating PPM1A. Journal of Cellular Biochemistry, 120(8), 13372-13381.

Cereijo, R., Gavaldà-Navarro, A., Cairó, M., Quesada-López, T., Villarroya, J., Morón-Ros, S., ... & Villarroya, F. (2018). CXCL14, a brown adipokine that mediates brown-fat-to-macrophage communication in thermogenic adaptation. Cell metabolism, 28(5), 750-763.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant CXCL14 protein (CAT#: V2LY-0526-LY2405)

Human Recombinant CXCL14 protein, His Tag (CAT#: V2LY-0526-LY2406)

Mouse Recombinant CXCL14 protein (CAT#: V2LY-0526-LY7881)

Human CXCL14 ELISA Kit (CAT#: V2LY-0626-LY3859)

Related Products

Rat Anti-CXCL14 Recombinant Antibody (C3436) (CAT#: CBMAB-C3436-LY)

Human CXCL14 ELISA Kit (CAT#: V2LY-0626-LY3859)

Human Recombinant CXCL14 protein (CAT#: V2LY-0526-LY2405)

Human Recombinant CXCL14 protein, His Tag (CAT#: V2LY-0526-LY2406)

Mouse Recombinant CXCL14 protein (CAT#: V2LY-0526-LY7881)

Rat Anti-CXCL14 Recombinant Antibody (CBXC-1494) (CAT#: V2LY-0125-LY671)

Mouse Anti-CXCL14 Recombinant Antibody (CBXC-0970) (CAT#: V2LY-0125-LY672)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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