DMBX1

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Full Name

diencephalon/mesencephalon homeobox 1

Function

Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development (By similarity).

Biological Process

Adult feeding behavior Source: Ensembl
Adult locomotory behavior Source: Ensembl
Brain development Source: UniProtKB
Central nervous system development Source: UniProtKB
Developmental growth Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central

Cellular Location

Nucleus

Anti-DMBX1 antibodies

Mouse Anti-DMBX1 Recombinant Antibody (CBXO-0337) (CBMAB-O0164-CQ)

Datasheet

SDS

Target: DMBX1

Host: Mouse

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: CBXO-0337

Application*: WB, IP, IF, E

Mouse Anti-DMBX1 Monoclonal Antibody (1A9) (CBMAB-1033-YC)

Datasheet

SDS

Target: DMBX1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 1A9

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)