DNAJC1

The membrane protein encoded by this gene is a DNAJ-like heat shock protein that binds the molecular chaperone BiP. In addition, the encoded protein contains two SANT domains that have been shown to bind serpin alpha1-antichymotrypsin and inter-alpha trypsin inhibitor heavy chain 4.

Full Name

DnaJ Heat Shock Protein Family (Hsp40) Member C1

Function

May modulate protein synthesis.

Biological Process

Negative regulation of proteolysis Source: UniProtKB
Protein folding Source: Ensembl
Regulation of protein secretion Source: UniProtKB
Regulation of translation Source: Ensembl

Cellular Location

Endoplasmic reticulum membrane; Microsome membrane; Nucleus membrane

Topology

Lumenal: 48-153
Helical: 154-174
Cytoplasmic: 175-554

Anti-DNAJC1 antibodies

Mouse Anti-DNAJC1 Recombinant Antibody (D-10) (CBMAB-D1303-YC)

Datasheet

SDS

Target: DNAJC1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: D-10

Application*: WB, IP, IF, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)