Mouse Anti-DNAJC1 Recombinant Antibody (D-10) (CBMAB-D1303-YC)

Name: Mouse Anti-DNAJC1 Recombinant Antibody (D-10)
SKU: CBMAB-D1303-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

D-10

Application

WB, IP, IF, ELISA

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

DnaJ Heat Shock Protein Family (Hsp40) Member C1

Introduction

DNAJC1 is a DNAJ-like heat shock protein that binds the molecular chaperone BiP. In addition, the encoded protein contains two SANT domains that have been shown to bind serpin alpha1-antichymotrypsin and inter-alpha trypsin inhibitor heavy chain 4.

Entrez Gene ID

64215

UniProt ID

Q96KC8

Alternative Names

DnaJ Heat Shock Protein Family (Hsp40) Member C1; DnaJ (Hsp40) Homolog, Subfamily C, Member 1; DnaJ Protein Homolog MTJ1; HTJ1; DnaJ Homolog Subfamily C Member 1; DnaJ-Like Protein; DNAJL1; ERdj1; MTJ1;

Function

May modulate protein synthesis.

Biological Process

Negative regulation of proteolysis Source: UniProtKB
Protein folding Source: Ensembl
Regulation of protein secretion Source: UniProtKB
Regulation of translation Source: Ensembl

Cellular Location

Endoplasmic reticulum membrane; Microsome membrane; Nucleus membrane

Topology

Lumenal: 48-153
Helical: 154-174
Cytoplasmic: 175-554

Wang, L. (2022). DNAJC1 inhibits ferroptosis by reducing ubiquitination of GPx4 in glioma cells. Brain Tumor Research and Treatment, 10(Suppl).

Meyer, N. J., Reilly, J. P., Anderson, B. J., Palakshappa, J. A., Shashaty, M. G., Ittner, C. A., ... & Christie, J. D. (2017). Genome Wide Analysis Of Sepsis-Associated Ards Implicates Dna J Heat Shock C1 (dnajc1). In C96. CRITICAL CARE: NEW DISCOVERIES IN ARDS (pp. A6750-A6750). American Thoracic Society.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-DNAJC1 Recombinant Antibody (D1303) (CAT#: V2LY-0425-LY644)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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