DNAJC27
DNAJC27 (DnaJ Heat Shock Protein Family (Hsp40) Member C27) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB18.
Full Name
DnaJ (Hsp40) homolog, subfamily C, member 27
Function
GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
Biological Process
Intracellular protein transport Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: Ensembl
Regulation of MAPK export from nucleus Source: Ensembl
Positive regulation of ERK1 and ERK2 cascade Source: Ensembl
Regulation of MAPK export from nucleus Source: Ensembl
Cellular Location
Nucleus
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Anti-DNAJC27 antibodies
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Target: DNAJC27
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3C1
Application*: E, WB
Target: DNAJC27
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 3C1
Application*: E, WB
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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