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DNAJC27

DNAJC27 (DnaJ Heat Shock Protein Family (Hsp40) Member C27) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB18.

Full Name

DnaJ (Hsp40) homolog, subfamily C, member 27

Function

GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.

Biological Process

Intracellular protein transport Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: Ensembl
Regulation of MAPK export from nucleus Source: Ensembl

Cellular Location

Nucleus

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Anti-DNAJC27 antibodies

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Mouse Anti-DNAJC27 Recombinant Antibody (3C1) (CBMAB-D1314-YC)

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Target: DNAJC27

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3C1

Application*: E, WB

Mouse Anti-DNAJC27 Recombinant Antibody (3C1) (V2LY-0425-LY654)

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Target: DNAJC27

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human, Mouse, Rat

Clone: 3C1

Application*: E, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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