EVE

Even skipped (Eve) is a homeobox-containing transcriptional repressor that acts in concert with co-repressors such as gro and Gug. Eve represses pair-rule and segment polarity genes, contributing to anterior/posterior axis specification and mesoderm and central nervous system development. The protein may play a role in determining neuronal identity, and may be directly involved in specifying identity of individual neurons.

Full Name

Even Skipped

Research Area

May play a role in determining neuronal identity. May be directly involved in specifying identity of individual neurons. Pair-rule protein required for segmentation; involved in transforming the broad, spatial, aperiodic expression patterns of the gap genes into a system of precise periodic expression patterns of the pair-rule and segmentary polarity genes.

Biological Process

Adult heart development Source: FlyBase
Blastoderm segmentation Source: FlyBase
Cephalic furrow formation Source: FlyBase
Germ-band extension Source: FlyBase
Heart morphogenesis Source: FlyBase
Motor neuron axon guidance Source: FlyBase
Negative regulation of cardioblast cell fate specification Source: FlyBase
Negative regulation of transcription by RNA polymerase II Source: FlyBase
Periodic partitioning by pair rule gene Source: FlyBase
Positive regulation of transcription by RNA polymerase II Source: FlyBase
Posterior head segmentation Source: FlyBase
Regulation of axonogenesis Source: FlyBase
Regulation of myoblast fusion Source: FlyBase
Regulation of transcription by RNA polymerase II Source: GO_Central
Trunk segmentation Source: FlyBase

Cellular Location

Nucleus