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Mouse Anti-EVE Monoclonal Antibody (3C10) (CBMAB-0175-CN)

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Datasheet
SDS
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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
3C10
Application
IHC
Immunogen
C-terminal 2/3 of even-skipped.
Host Species
Mouse
Specificity
Common fruit fly
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
IHC0.2-0.5 μg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Even Skipped
Introduction
Even skipped (Eve) is a homeobox-containing transcriptional repressor that acts in concert with co-repressors such as gro and Gug. Eve represses pair-rule and segment polarity genes, contributing to anterior/posterior axis specification and mesoderm and central nervous system development. The protein may play a role in determining neuronal identity, and may be directly involved in specifying identity of individual neurons.
Entrez Gene ID
36039
UniProt ID
P06602
Alternative Names
10.5; 10.9; 14.10; 20.35; CG2328; dm-eve; Dmel\CG2328; E(eve); Eve; EVE; eve2; even; F; l(2)46Ce; l(2)46CFg; l(2)46CFh; l(2)46CFj; l(2)46CFp; l(2)46Cg; V; VI
Research Area
May play a role in determining neuronal identity. May be directly involved in specifying identity of individual neurons. Pair-rule protein required for segmentation; involved in transforming the broad, spatial, aperiodic expression patterns of the gap genes into a system of precise periodic expression patterns of the pair-rule and segmentary polarity genes.
Biological Process
Adult heart development Source: FlyBase
Blastoderm segmentation Source: FlyBase
Cephalic furrow formation Source: FlyBase
Germ-band extension Source: FlyBase
Heart morphogenesis Source: FlyBase
Motor neuron axon guidance Source: FlyBase
Negative regulation of cardioblast cell fate specification Source: FlyBase
Negative regulation of transcription by RNA polymerase II Source: FlyBase
Periodic partitioning by pair rule gene Source: FlyBase
Positive regulation of transcription by RNA polymerase II Source: FlyBase
Posterior head segmentation Source: FlyBase
Regulation of axonogenesis Source: FlyBase
Regulation of myoblast fusion Source: FlyBase
Regulation of transcription by RNA polymerase II Source: GO_Central
Trunk segmentation Source: FlyBase
Cellular Location
Nucleus
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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