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Mouse Anti-EVE Recombinant Antibody (2B8) (CBMAB-0127-CN)

This product is a mouse antibody that recognizes EVE of Grasshopper. The antibody 2B8 can be used for immunoassay techniques such as: IHC.
See all EVE antibodies

Summary

Host Animal
Mouse
Specificity
Grasshopper, Common fruit fly, Insect
Clone
2B8
Antibody Isotype
IgG1
Application
IHC

Basic Information

Immunogen
C-terminal 2/3 of even-skipped.
Specificity
Grasshopper, Common fruit fly, Insect
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Even Skipped
Introduction
Even skipped (Eve) is a homeobox-containing transcriptional repressor that acts in concert with co-repressors such as gro and Gug. Eve represses pair-rule and segment polarity genes, contributing to anterior/posterior axis specification and mesoderm and central nervous system development. The protein may play a role in determining neuronal identity, and may be directly involved in specifying identity of individual neurons.
Entrez Gene ID
UniProt ID
Alternative Names
10.5; 10.9; 14.10; 20.35; CG2328; dm-eve; Dmel\CG2328; E(eve); Eve; EVE; eve2; even; F; l(2)46Ce; l(2)46CFg; l(2)46CFh; l(2)46CFj; l(2)46CFp; l(2)46Cg; V; VI
Research Area
May play a role in determining neuronal identity. May be directly involved in specifying identity of individual neurons. Pair-rule protein required for segmentation; involved in transforming the broad, spatial, aperiodic expression patterns of the gap genes into a system of precise periodic expression patterns of the pair-rule and segmentary polarity genes.
Biological Process
Adult heart development Source: FlyBase
Blastoderm segmentation Source: FlyBase
Cephalic furrow formation Source: FlyBase
Germ-band extension Source: FlyBase
Heart morphogenesis Source: FlyBase
Motor neuron axon guidance Source: FlyBase
Negative regulation of cardioblast cell fate specification Source: FlyBase
Negative regulation of transcription by RNA polymerase II Source: FlyBase
Periodic partitioning by pair rule gene Source: FlyBase
Positive regulation of transcription by RNA polymerase II Source: FlyBase
Posterior head segmentation Source: FlyBase
Regulation of axonogenesis Source: FlyBase
Regulation of myoblast fusion Source: FlyBase
Regulation of transcription by RNA polymerase II Source: GO_Central
Trunk segmentation Source: FlyBase
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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