FKBP2

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Full Name
FK506 Binding Protein 2
Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Biological Process
Chaperone-mediated protein folding Source: InterPro
Cellular Location
Endoplasmic reticulum membrane
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Anti-FKBP2 antibodies

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Target: FKBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: 33B
Application*: ELISA, IHC, WB
Target: FKBP2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CF169
Application*: ELISA, WB, IHC
Target: FKBP2
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBXF-3047
Application*: E, WB
Target: FKBP2
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBXF-2642
Application*: WB
Target: FKBP2
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-0707
Application*: E, WB
Target: FKBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig, Rat
Clone: CBXF-2288
Application*: E, WB, IH
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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