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FUT4 (Concentrate)

The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq, Jan 2009]

Full Name

Fucosyltransferase 4

Function

May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.

Biological Process

Carbohydrate metabolic process Source: ProtInc
Fucosylation Source: GO_Central
L-fucose catabolic process Source: UniProtKB
Oligosaccharide biosynthetic process Source: Reactome
Oligosaccharide metabolic process Source: UniProtKB
Positive regulation of leukocyte tethering or rolling Source: UniProtKB
Protein glycosylation Source: UniProtKB
Regulation of leukocyte cell-cell adhesion Source: UniProtKB

Cellular Location

Golgi stack membrane. Membrane-bound form in trans cisternae of Golgi.

Topology

Cytoplasmic: 1-147
Helical: 148-172
Lumenal: 173-530

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Anti-FUT4 (Concentrate) antibodies

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Mouse Anti-FUT4 (Concentrate) Antibody (CB068) (CBMAB-AL068LY)

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Target: FUT4 (Concentrate)

Host: Mouse

Antibody Isotype: IgM

Specificity: Human

Clone: CB068

Application*: IVD

Mouse Anti-FUT4 (Concentrate) Antibody (CB067) (CBMAB-AL067LY)

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Target: FUT4 (Concentrate)

Host: Mouse

Antibody Isotype: IgM

Specificity: Human

Clone: CB067

Application*: IVD

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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