GAPDHS
This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008]
Full Name
Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic
Function
May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity).
Biological Process
Flagellated sperm motility Source: UniProtKB
Glucose metabolic process Source: InterPro
Glycolytic process Source: GO_Central
Positive regulation of glycolytic process Source: UniProtKB
Glucose metabolic process Source: InterPro
Glycolytic process Source: GO_Central
Positive regulation of glycolytic process Source: UniProtKB
Cellular Location
Cytoplasm
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Anti-GAPDHS antibodies
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Target: GAPDHS
Host: Mouse
Antibody Isotype: IgM
Specificity: Human, Mouse, Rat, Pig, Cattle
Application*: ELISA, WB, IF
Target: GAPDHS
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2E3-2E10
Application*: WB, E
Target: GAPDHS
Host: Mouse
Antibody Isotype: IgM
Specificity: Pig, Human, Mouse, Rat
Clone: 1D4
Application*: WB
Target: GAPDHS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-642
Application*: E, P, WB
Target: GAPDHS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-641
Application*: WB
Target: GAPDHS
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-2581
Application*: WB
Target: GAPDHS
Host: Mouse
Antibody Isotype: IgM
Specificity: Human, Pig
Clone: Hs-8
Application*: F
Target: GAPDHS
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2E3-2E10
Application*: E, WB, IH
Target: GAPDHS
Host: Mouse
Antibody Isotype: IgM
Specificity: Human, Pig
Clone: 1F6
Application*: WB, IF, F
Target: GAPDHS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-036
Application*: E, IH, WB
Target: GAPDHS
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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