GATAD1
The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene.
Full Name
GATA Zinc Finger Domain Containing 1
Function
Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3).
Biological Process
Chromatin organization Source: GO_Central
Chromatin remodeling Source: GO_Central
Regulation of transcription, DNA-templated Source: InterPro
Chromatin remodeling Source: GO_Central
Regulation of transcription, DNA-templated Source: InterPro
Cellular Location
Nucleus
Involvement in disease
Cardiomyopathy, dilated 2B (CMD2B):
A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
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Anti-GATAD1 antibodies
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Target: GATAD1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: GATA9A1D3
Application*: DB, F, IC, IF, WB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2618
Application*: WB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: 8C155
Application*: WB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 459C1a
Application*: DB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-0260
Application*: WB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-0259
Application*: WB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0258
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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