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GATAD1

The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene.
Full Name
GATA Zinc Finger Domain Containing 1
Function
Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3).
Biological Process
Chromatin organization Source: GO_Central
Chromatin remodeling Source: GO_Central
Regulation of transcription, DNA-templated Source: InterPro
Cellular Location
Nucleus
Involvement in disease
Cardiomyopathy, dilated 2B (CMD2B):
A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Anti-GATAD1 antibodies

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Target: GATAD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 459C1a
Application*: DB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: 8C155
Application*: WB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2618
Application*: WB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: GATA9A1D3
Application*: DB, F, IC, IF, WB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0258
Application*: WB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-0259
Application*: WB
Target: GATAD1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-0260
Application*: WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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