Mouse Anti-GATAD1 Monoclonal Antibody (GATA9A1D3) (CBMAB-1433-YC)

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
GATA9A1D3
Application
Dot, FC, ICC, IF, WB
Immunogen
Recombinant human fragment
Specificity
Human, Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
GATA Zinc Finger Domain Containing 1
Introduction
GATAD1 contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in GATAD1 have been associated with autosomal recessive dilated cardiomyopathy.
Entrez Gene ID
Human57798
Mouse67210
UniProt ID
HumanQ8WUU5
MouseQ920S3
Function
Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3).
Biological Process
Chromatin organization Source: GO_Central
Chromatin remodeling Source: GO_Central
Regulation of transcription, DNA-templated Source: InterPro
Cellular Location
Nucleus
Involvement in disease
Cardiomyopathy, dilated 2B (CMD2B):
A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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