GEM

The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq]
Full Name
GTP binding protein overexpressed in skeletal muscle
Function
Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
Biological Process
Cell surface receptor signaling pathway Source: ProtInc
Chromosome organization Source: UniProtKB
Immune response Source: ProtInc
Metaphase plate congression Source: UniProtKB
Mitotic cell cycle Source: UniProtKB
Negative regulation of high voltage-gated calcium channel activity Source: InterPro
Signal transduction Source: ProtInc
Cellular Location
Cell membrane
PTM
Phosphorylated on tyrosine residues.
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Anti-GEM antibodies

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Mouse Anti-GEM Recombinant Antibody (CBLG1-3160) (CBMAB-G2792-LY)

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Target: GEM
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-3160
Application*: WB
Datasheet SDS

Mouse Anti-GEM Recombinant Antibody (4B12) (CBMAB-G2791-LY)

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Target: GEM
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4B12
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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