GJB7
Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008]
Full Name
Gap Junction Protein Beta 7
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Biological Process
Cell-cell signaling Source: GO_Central
Transmembrane transport Source: UniProtKB
Transmembrane transport Source: UniProtKB
Cellular Location
Cell membrane; Gap junction
Topology
Cytoplasmic: 1-19
Helical: 20-40
Extracellular: 41-75
Helical: 76-96
Cytoplasmic: 97-121
Helical: 122-142
Extracellular: 143-177
Helical: 178-198
Cytoplasmic: 199-223
Helical: 20-40
Extracellular: 41-75
Helical: 76-96
Cytoplasmic: 97-121
Helical: 122-142
Extracellular: 143-177
Helical: 178-198
Cytoplasmic: 199-223
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Anti-GJB7 antibodies
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Target: GJB7
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1320
Application*: WB: 1:500~1:1000 ELISA: 1:10000
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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