GP9

GP9 (Glycoprotein IX Platelet) is a Protein Coding gene. Diseases associated with GP9 include Bernard-Soulier Syndrome and Blood Platelet Disease. Among its related pathways are Integrin alphaIIb beta3 signaling and GP1b-IX-V activation signalling. An important paralog of this gene is GP1BB.
Full Name
Glycoprotein IX Platelet
Function
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
Biological Process
Blood coagulation Source: ProtInc
Cell adhesion Source: ProtInc
Cellular Location
Membrane
Involvement in disease
Bernard-Soulier syndrome (BSS):
A coagulation disorder characterized by a prolonged bleeding time, unusually large platelets, thrombocytopenia, and impaired prothrombin consumption.
Topology
Extracellular: 17-147
Helical: 148-168
Cytoplasmic: 169-177
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Anti-GP9 antibodies

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Mouse Anti-GP9 Recombinant Antibody (SZ1) (CBMAB-C11632-LY)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: SZ1
Application*: IF/IC, IP, F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (CBLG1-187) (CBMAB-G0661-LY)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-187
Application*: F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (ESS) (CBMAB-H0601-FY)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: ESS
Application*: F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (6D267) (CBMAB-C3532-CN)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6D267
Application*: FC, IH, IP
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (2Q1339) (CBMAB-C3531-CN)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2Q1339
Application*: FC, IF, IH
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (3H1304) (CBMAB-C1165-LY)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1304
Application*: P, F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (FMC-25) (CBMAB-G0659-LY)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: FMC-25
Application*: C, F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (14D38) (CBMAB-G0657-LY)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 14D38
Application*: F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (CBT4409) (V2LY-0625-LY1704)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4409
Application*: WB, IH, F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (CBT3242) (V2LY-0625-LY1682)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3242
Application*: WB, IH, F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (CBT4022) (V2LY-0625-LY1042)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4022
Application*: F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (CBWJC-3744) (CBMAB-C5009WJ)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3744
Application*: F, IC, IP
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (CBWJC-3743) (CBMAB-C5008WJ)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3743
Application*: C, F
Datasheet SDS

Rabbit Anti-GP9 Recombinant Antibody (CBWJC-3742) (CBMAB-C5007WJ)

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Target: GP9
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-3742
Application*: WB
Datasheet SDS

Human Anti-GP9 Recombinant Antibody (CBXC-0746) (CBMAB-C1860-CQ)

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Target: GP9
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0746
Application*: F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (CBYY-C2525) (CBMAB-C3966-YY)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2525
Application*: F, IH
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (GRP-P) (CBMAB-H1303-FY)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog
Clone: GRP-P
Application*: F
Datasheet SDS

Mouse Anti-GP9 Recombinant Antibody (CBFYH-0431) (CBMAB-H0602-FY)

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Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0431
Application*: IF, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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