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GP9

GP9 (Glycoprotein IX Platelet) is a Protein Coding gene. Diseases associated with GP9 include Bernard-Soulier Syndrome and Blood Platelet Disease. Among its related pathways are Integrin alphaIIb beta3 signaling and GP1b-IX-V activation signalling. An important paralog of this gene is GP1BB.
Full Name
Glycoprotein IX Platelet
Function
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
Biological Process
Blood coagulation Source: ProtInc
Cell adhesion Source: ProtInc
Cellular Location
Membrane
Involvement in disease
Bernard-Soulier syndrome (BSS):
A coagulation disorder characterized by a prolonged bleeding time, unusually large platelets, thrombocytopenia, and impaired prothrombin consumption.
Topology
Extracellular: 17-147
Helical: 148-168
Cytoplasmic: 169-177

Anti-GP9 antibodies

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Mouse Anti-GP9 Recombinant Antibody (SZ1) (CBMAB-C11632-LY)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: SZ1
Application*: IF/IC, IP, F

Mouse Anti-GP9 Recombinant Antibody (6D267) (CBMAB-C3532-CN)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6D267
Application*: FC, IH, IP

Mouse Anti-GP9 Recombinant Antibody (2Q1339) (CBMAB-C3531-CN)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2Q1339
Application*: FC, IF, IH

Mouse Anti-GP9 Recombinant Antibody (3H1304) (CBMAB-C1165-LY)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1304
Application*: P, F

Mouse Anti-GP9 Recombinant Antibody (CBLG1-187) (CBMAB-G0661-LY)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-187
Application*: F

Mouse Anti-GP9 Recombinant Antibody (FMC-25) (CBMAB-G0659-LY)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: FMC-25
Application*: C, F

Mouse Anti-GP9 Recombinant Antibody (14D38) (CBMAB-G0657-LY)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 14D38
Application*: F

Mouse Anti-GP9 Recombinant Antibody (CBWJC-3744) (CBMAB-C5009WJ)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3744
Application*: F, IC, IP

Mouse Anti-GP9 Recombinant Antibody (CBWJC-3743) (CBMAB-C5008WJ)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3743
Application*: C, F

Rabbit Anti-GP9 Recombinant Antibody (CBWJC-3742) (CBMAB-C5007WJ)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-3742
Application*: WB

Human Anti-GP9 Recombinant Antibody (CBXC-0746) (CBMAB-C1860-CQ)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0746
Application*: F

Mouse Anti-GP9 Recombinant Antibody (CBYY-C2525) (CBMAB-C3966-YY)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2525
Application*: F, IH

Mouse Anti-GP9 Recombinant Antibody (GRP-P) (CBMAB-H1303-FY)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog
Clone: GRP-P
Application*: F

Mouse Anti-GP9 Recombinant Antibody (CBFYH-0431) (CBMAB-H0602-FY)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0431
Application*: IF, IH

Mouse Anti-GP9 Recombinant Antibody (ESS) (CBMAB-H0601-FY)

Datasheet Datasheet SDS SDS
Target: GP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: ESS
Application*: F
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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