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Mouse Anti-GP9 Recombinant Antibody (14D38) (CBMAB-G0657-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
14D38
Antibody Isotype
IgG2a
Application
FC

Basic Information

Immunogen
Corresponding to human CD42A from Washed human platelets
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Glycoprotein IX Platelet
Entrez Gene ID
2815
UniProt ID
P14770
Alternative Names
Glycoprotein IX Platelet; Platelet Glycoprotein IX; Glycoprotein 9; GPIX; Glycoprotein IX (Platelet); CD42a Antigen; CD42a; GP-IX;
Function
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
Biological Process
Blood coagulation Source: ProtInc
Cell adhesion Source: ProtInc
Cellular Location
Membrane
Involvement in disease
Bernard-Soulier syndrome (BSS):
A coagulation disorder characterized by a prolonged bleeding time, unusually large platelets, thrombocytopenia, and impaired prothrombin consumption.
Topology
Extracellular: 17-147
Helical: 148-168
Cytoplasmic: 169-177
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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