Mouse Anti-GP9 Recombinant Antibody (CBT3242) (V2LY-0625-LY1682)

Name: Mouse Anti-GP9 Recombinant Antibody (CBT3242)
SKU: V2LY-0625-LY1682
Rating: 5 (1 reviews)

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Tested Data

Mouse Anti-GP9 Recombinant Antibody (CBT3242) (V2LY-0625-LY1682) in ELISA

Mouse Anti-GP9 Recombinant Antibody (CBT3242) (V2LY-0625-LY1682) in WB

Mouse Anti-GP9 Recombinant Antibody (CBT3242) (V2LY-0625-LY1682) in FC

Mouse Anti-GP9 Recombinant Antibody (CBT3242) (V2LY-0625-LY1682) in IHC

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBT3242

Application

WB, IHC, FC

Immunogen

Purified recombinant fragment of human CD42A (AA: extra(17-147)) expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
IHC-P	1:200-1:1,000
FC	1:200-1:400
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Glycoprotein IX Platelet

Entrez Gene ID

2815

UniProt ID

P14770

Function

The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.

Biological Process

Blood coagulation Source: ProtInc
Cell adhesion Source: ProtInc

Cellular Location

Membrane

Involvement in disease

Bernard-Soulier syndrome (BSS):
A coagulation disorder characterized by a prolonged bleeding time, unusually large platelets, thrombocytopenia, and impaired prothrombin consumption.

Topology

Extracellular: 17-147
Helical: 148-168
Cytoplasmic: 169-177

Gentilini, F., Turba, M. E., Giancola, F., Chiocchetti, R., Bernardini, C., Dajbychova, M., ... & Drögemüller, C. (2019). A large deletion in the GP9 gene in Cocker Spaniel dogs with Bernard-Soulier syndrome. Plos one, 14(9), e0220625.

Boisseau, P., Debord, C., Eveillard, M., Quéméner, A., Sigaud, M., Giraud, M., ... & Fouassier, M. (2018). Two novel variants of uncertain significance in GP9 associated with Bernard–Soulier syndrome: Are they true mutations?. Platelets, 29(3), 316-318.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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