GPR12

Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.
Full Name
G protein-coupled receptor 12
Function
Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).

Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.
Biological Process
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: GO_Central
Cellular calcium ion homeostasis Source: Ensembl
G protein-coupled receptor signaling pathway Source: ProtInc
Regulation of metabolic process Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-48
Helical: 49-69
Cytoplasmic: 70-77
Helical: 78-98
Extracellular: 99-113
Helical: 114-134
Cytoplasmic: 135-158
Helical: 159-179
Extracellular: 180-199
Helical: 200-220
Cytoplasmic: 221-252
Helical: 253-273
Extracellular: 274-282
Helical: 283-303
Cytoplasmic: 304-334
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Anti-GPR12 antibodies

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Target: GPR12
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1367
Application*: IF: 1:100~1:500 ELISA: 1:5000
Target: GPR12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 584940
Application*: IH
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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