GPR12

Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.

Full Name

G protein-coupled receptor 12

Function

Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).

Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.

Biological Process

Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: GO_Central
Cellular calcium ion homeostasis Source: Ensembl
G protein-coupled receptor signaling pathway Source: ProtInc
Regulation of metabolic process Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-48
Helical: 49-69
Cytoplasmic: 70-77
Helical: 78-98
Extracellular: 99-113
Helical: 114-134
Cytoplasmic: 135-158
Helical: 159-179
Extracellular: 180-199
Helical: 200-220
Cytoplasmic: 221-252
Helical: 253-273
Extracellular: 274-282
Helical: 283-303
Cytoplasmic: 304-334

Anti-GPR12 antibodies

Mouse Anti-GPR12 Recombinant Antibody (584940) (CBMAB-G4630-LY)

Datasheet

SDS

Target: GPR12

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 584940

Application*: IH

Rabbit Anti-GPR12 Recombinant Antibody (EG1367) (CBMAB-EN1646-LY)

Datasheet

SDS

Target: GPR12

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1367

Application*: IF: 1:100~1:500 ELISA: 1:5000

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)