GPR12
Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.
Full Name
G protein-coupled receptor 12
Function
Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).
Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.
Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.
Biological Process
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: GO_Central
Cellular calcium ion homeostasis Source: Ensembl
G protein-coupled receptor signaling pathway Source: ProtInc
Regulation of metabolic process Source: GO_Central
Cellular calcium ion homeostasis Source: Ensembl
G protein-coupled receptor signaling pathway Source: ProtInc
Regulation of metabolic process Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-48
Helical: 49-69
Cytoplasmic: 70-77
Helical: 78-98
Extracellular: 99-113
Helical: 114-134
Cytoplasmic: 135-158
Helical: 159-179
Extracellular: 180-199
Helical: 200-220
Cytoplasmic: 221-252
Helical: 253-273
Extracellular: 274-282
Helical: 283-303
Cytoplasmic: 304-334
Helical: 49-69
Cytoplasmic: 70-77
Helical: 78-98
Extracellular: 99-113
Helical: 114-134
Cytoplasmic: 135-158
Helical: 159-179
Extracellular: 180-199
Helical: 200-220
Cytoplasmic: 221-252
Helical: 253-273
Extracellular: 274-282
Helical: 283-303
Cytoplasmic: 304-334
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Anti-GPR12 antibodies
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CompareTarget: GPR12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 40
Application*: IH, F
Target: GPR12
Sensitivity: 0.25 ng/mL
Detection Range: 0.5-100 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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