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GPR12

Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.

Full Name

G protein-coupled receptor 12

Function

Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).

Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.

Biological Process

Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: GO_Central
Cellular calcium ion homeostasis Source: Ensembl
G protein-coupled receptor signaling pathway Source: ProtInc
Regulation of metabolic process Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-48
Helical: 49-69
Cytoplasmic: 70-77
Helical: 78-98
Extracellular: 99-113
Helical: 114-134
Cytoplasmic: 135-158
Helical: 159-179
Extracellular: 180-199
Helical: 200-220
Cytoplasmic: 221-252
Helical: 253-273
Extracellular: 274-282
Helical: 283-303
Cytoplasmic: 304-334

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Anti-GPR12 antibodies

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Mouse Anti-GPR12 Recombinant Antibody (40) (CBMAB-G4630-LY)

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Target: GPR12

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 40

Application*: IH, F

Human GPR12 ELISA Kit (V2LY-0626-LY3379)

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Target: GPR12

Sensitivity: 0.25 ng/mL

Detection Range: 0.5-100 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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