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Mouse Anti-GPR12 Recombinant Antibody (584940) (CBMAB-G4630-LY)

This product is antibody recognizes GPR12. The antibody 584940 immunoassay techniques such as: IHC.
See all GPR12 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
584940
Antibody Isotype
IgG1
Application
IHC

Basic Information

Immunogen
NS0 mouse myeloma cell line transfected with human GPR12, Met1-Val334, Accession # P47775
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
lyophilized
Buffer
Trehalose
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
G protein-coupled receptor 12
Entrez Gene ID
UniProt ID
Alternative Names
GPCR12; GPCR21; PPP1R84
Function
Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).

Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.
Biological Process
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: GO_Central
Cellular calcium ion homeostasis Source: Ensembl
G protein-coupled receptor signaling pathway Source: ProtInc
Regulation of metabolic process Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-48
Helical: 49-69
Cytoplasmic: 70-77
Helical: 78-98
Extracellular: 99-113
Helical: 114-134
Cytoplasmic: 135-158
Helical: 159-179
Extracellular: 180-199
Helical: 200-220
Cytoplasmic: 221-252
Helical: 253-273
Extracellular: 274-282
Helical: 283-303
Cytoplasmic: 304-334
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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