GPR15

This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane.

Full Name

G Protein-Coupled Receptor 15

Function

Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection.

Biological Process

G protein-coupled receptor signaling pathway Source: UniProtKB
T cell migration Source: Ensembl
Viral entry into host cell Source: UniProtKB

Cellular Location

Cell membrane

Topology

Extracellular: 1-33
Helical: 34-54
Cytoplasmic: 55-69
Helical: 70-90
Extracellular: 91-120
Helical: 121-141
Cytoplasmic: 142-149
Helical: 150-170
Extracellular: 171-192
Helical: 193-213
Cytoplasmic: 214-239
Helical: 240-260
Extracellular: 261-284
Helical: 285-305
Cytoplasmic: 306-360

Anti-GPR15 antibodies

Mouse Anti-GPR15 Recombinant Antibody (367902) (CBMAB-G0706-LY)

Datasheet

SDS

Target: GPR15

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 367902

Application*: F

Mouse Anti-GPR15 Recombinant Antibody (SA302A10) (CBMAB-G0707-LY)

Datasheet

SDS

Target: GPR15

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: SA302A10

Application*: F

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)