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GPR50

This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]

Full Name

G Protein-Coupled Receptor 50

Function

Does not bind melatonin.

Biological Process

Cell-cell signaling Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-30
Helical: 31-51
Cytoplasmic: 52-64
Helical: 65-85
Extracellular: 86-103
Helical: 104-124
Cytoplasmic: 125-143
Helical: 144-164
Extracellular: 165-188
Helical: 189-209
Cytoplasmic: 210-239
Helical: 240-260
Extracellular: 261-273
Helical: 274-294
Cytoplasmic: 295-617

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Anti-GPR50 antibodies

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Rabbit Anti-GPR50 Recombinant Antibody (1D6) (CBMAB-G4663-LY)

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Target: GPR50

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 1D6

Application*: WB

Mouse Anti-GPR50 Recombinant Antibody (CBFYH-0460) (CBMAB-H1332-FY)

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Target: GPR50

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYH-0460

Application*: IH

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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