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GPR50

This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
Full Name
G Protein-Coupled Receptor 50
Function
Does not bind melatonin.
Biological Process
Cell-cell signaling Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-30
Helical: 31-51
Cytoplasmic: 52-64
Helical: 65-85
Extracellular: 86-103
Helical: 104-124
Cytoplasmic: 125-143
Helical: 144-164
Extracellular: 165-188
Helical: 189-209
Cytoplasmic: 210-239
Helical: 240-260
Extracellular: 261-273
Helical: 274-294
Cytoplasmic: 295-617
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Anti-GPR50 antibodies

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Rabbit Anti-GPR50 Recombinant Antibody (D1D6I) (CBMAB-G4663-LY)

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Target: GPR50
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D1D6I
Application*: WB
Datasheet SDS

Mouse Anti-GPR50 Recombinant Antibody (461129) (CBMAB-G0720-LY)

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Target: GPR50
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 461129
Application*: F
Datasheet SDS

Mouse Anti-GPR50 Recombinant Antibody (CBFYH-0460) (CBMAB-H1332-FY)

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Target: GPR50
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0460
Application*: P
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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