HHIP

This gene encodes a protein similar to the mouse hedgehog-interacting protein, a regulatory component of the hedgehog signalling pathway. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic development, including anteroposterior patterns of limbs and regulation of left-right asymmetry. [provided by RefSeq]
Full Name
hedgehog interacting protein
Function
Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family.
Biological Process
Dorsal/ventral pattern formation Source: Ensembl
Epithelial tube branching involved in lung morphogenesis Source: Ensembl
Negative regulation of apoptotic process Source: Ensembl
Negative regulation of signal transduction Source: UniProtKB
Negative regulation of smoothened signaling pathway Source: BHF-UCL
Neuroblast proliferation Source: Ensembl
Regulation of fibroblast growth factor receptor signaling pathway Source: Ensembl
Signal transduction Source: Ensembl
Skeletal system morphogenesis Source: BHF-UCL
Cellular Location
Cell membrane; Secreted. The last 22 C-terminal amino acids may participate in cell membrane attachment.
Isoform 2: Cytoplasm
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Anti-HHIP antibodies

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Mouse Anti-HHIP Recombinant Antibody (5D11) (CBMAB-A3889-LY)

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Target: HHIP
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 5D11
Application*: WB, E
Datasheet SDS

Mouse Anti-HHIP Recombinant Antibody (CBFYH-1064) (CBMAB-H2008-FY)

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Target: HHIP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-1064
Application*: WB
Datasheet SDS

Rat Anti-HHIP Recombinant Antibody (CBFYH-3561) (CBMAB-H4114-FY)

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Target: HHIP
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYH-3561
Application*: WB
Datasheet SDS

Mouse Anti-HHIP (AA 21-120) Recombinant Antibody (CBFYH-1063) (CBMAB-H2007-FY)

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Target: HHIP
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYH-1063
Application*: E, P, IP, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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