HIPK4

This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53.
Full Name
homeodomain interacting protein kinase 4
Function
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity).

May act as a corepressor of transcription factors (Potential).
Biological Process
Histone phosphorylation Source: Ensembl
Peptidyl-serine phosphorylation Source: GO_Central
Peptidyl-threonine phosphorylation Source: GO_Central
Protein autophosphorylation Source: Ensembl
Regulation of signal transduction by p53 class mediator Source: Ensembl
Cellular Location
Cytoplasm
PTM
Autophosphorylated.
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Anti-HIPK4 antibodies

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Mouse Anti-HIPK4 Recombinant Antibody (2E8) (CBMAB-A3914-LY)

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Target: HIPK4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E8
Application*: WB, E
Datasheet SDS

Mouse Anti-HIPK4 Monoclonal Antibody (CBFYH-3072) (CBMAB-H2088-FY)

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Target: HIPK4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBFYH-3072
Application*: WB, E
Datasheet SDS

Mouse Anti-HIPK4 Recombinant Antibody (CBFYH-1135) (CBMAB-H0682-FY)

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Target: HIPK4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-1135
Application*: E, WB
Datasheet SDS

Rabbit Anti-HIPK4 Recombinant Antibody (EG1513) (CBMAB-EN1808-LY)

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Target: HIPK4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1513
Application*: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:00~1:500 ELISA: 1:20000
Datasheet SDS

HIPK4 Matched Antibody Pair (543) (APMAB-543LY)

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Target: HIPK4
Specificity: Human
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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