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Rabbit Anti-HIPK4 Recombinant Antibody (EG1513) (CBMAB-EN1808-LY)

The product is antibody recognizes HIPK4. The antibody EG1513 immunoassay techniques such as: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:00~1:500 ELISA: 1:20000.
See all HIPK4 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1513
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:00~1:500 ELISA: 1:20000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human HIPK4.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
homeodomain interacting protein kinase 4
Introduction
This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53.
Entrez Gene ID
Human147746
Mouse233020
Rat308449
UniProt ID
HumanQ8NE63
MouseQ3V016
RatQ4V793
Function
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity).

May act as a corepressor of transcription factors (Potential).
Biological Process
Histone phosphorylation Source: Ensembl
Peptidyl-serine phosphorylation Source: GO_Central
Peptidyl-threonine phosphorylation Source: GO_Central
Protein autophosphorylation Source: Ensembl
Regulation of signal transduction by p53 class mediator Source: Ensembl
Cellular Location
Cytoplasm
PTM
Autophosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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